BDBM50202091 CHEMBL384364::N-adamantan-2-yl-2-[4-(3-cyano-pyridin-2-yl)-piperazin-1-yl]-acetamide

SMILES O=C(CN1CCN(CC1)c1ncccc1C#N)NC1C2CC3CC(C2)CC1C3

InChI Key InChIKey=LTTIAASWMSZBDG-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50202091   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202091(CHEMBL384364 | N-adamantan-2-yl-2-[4-(3-cyano-pyri...)
Affinity DataKi:  14nMAssay Description:Inhibition of human 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202091(CHEMBL384364 | N-adamantan-2-yl-2-[4-(3-cyano-pyri...)
Affinity DataKi:  53nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in E. coli by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202091(CHEMBL384364 | N-adamantan-2-yl-2-[4-(3-cyano-pyri...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against human 11beta-HSD2 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202091(CHEMBL384364 | N-adamantan-2-yl-2-[4-(3-cyano-pyri...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against mouse 11beta-HSD2 by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50202091(CHEMBL384364 | N-adamantan-2-yl-2-[4-(3-cyano-pyri...)
Affinity DataIC50:  260nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells by FPIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed