BDBM50202144 CHEMBL395644::N-(4-chloro-2-((4-ethoxy-1,3-dioxoisoindolin-2-yl)methyl)phenyl)picolinamide

SMILES CCOc1cccc2C(=O)N(Cc3cc(Cl)ccc3NC(=O)c3ccccn3)C(=O)c12

InChI Key InChIKey=GYFJSDOHDHLNJB-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50202144   

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50202144(CHEMBL395644 | N-(4-chloro-2-((4-ethoxy-1,3-dioxoi...)
Affinity DataEC50:  280nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed