BDBM50202274 2-[5-(diphenylmethylidene)-4-oxo-2-thioxothiazolidin-3-yl]-4-methylpentanoic acid::CHEMBL439400

SMILES CC(C)C[C@@H](C(=O)O)N1C(=O)C(=C(c2ccccc2)c2ccccc2)SC1=S

InChI Key InChIKey=YPIMXXIPEUIJMF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202274   

TargetApoptosis regulator Bcl-2(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202274BDBM50202274(2-[5-(diphenylmethylidene)-4-oxo-2-thioxothiazolid...)
Affinity DataKi:  5.78E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptotic Bcl2 protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetBcl-2-like protein 2(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202274BDBM50202274(2-[5-(diphenylmethylidene)-4-oxo-2-thioxothiazolid...)
Affinity DataKi:  6.19E+4nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptotic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed