BDBM50202276 2-propenyl 2-[5-biphenylmethylidene-4-oxo-2-thioxothiazolidin-3-yl]-3-phenylpropanoate::CHEMBL396500

SMILES C=CCOC(=O)[C@H](Cc1ccccc1)N1C(=O)C(=C(c2ccccc2)c2ccccc2)SC1=S

InChI Key InChIKey=PXAWAIKYGLRZNZ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50202276   

TargetBcl-2-like protein 2(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202276BDBM50202276(2-propenyl 2-[5-biphenylmethylidene-4-oxo-2-thioxo...)
Affinity DataKi:  1.16E+5nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptotic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Minnesota

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50202276BDBM50202276(2-propenyl 2-[5-biphenylmethylidene-4-oxo-2-thioxo...)
Affinity DataKi:  2.60E+5nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptotic Bcl2 protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed