BDBM50202401 (RR/SS)-2-[1-(4-chlorophenyl)-2-methylpropyl]piperidine::(RS/SR)-2-[1-(4-chlorophenyl)-2-methylpropyl]piperidine::CHEMBL218848

SMILES CC(C)C(C1CCCCN1)c1ccc(Cl)cc1

InChI Key InChIKey=SSUIQPFKMQJHGV-UHFFFAOYSA-N

Data  6 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50202401   

TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202401((RR/SS)-2-[1-(4-chlorophenyl)-2-methylpropyl]piper...)
Affinity DataKi:  46nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202401((RR/SS)-2-[1-(4-chlorophenyl)-2-methylpropyl]piper...)
Affinity DataKi:  46nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202401((RR/SS)-2-[1-(4-chlorophenyl)-2-methylpropyl]piper...)
Affinity DataKi:  810nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202401((RR/SS)-2-[1-(4-chlorophenyl)-2-methylpropyl]piper...)
Affinity DataKi:  5.30E+3nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202401((RR/SS)-2-[1-(4-chlorophenyl)-2-methylpropyl]piper...)
Affinity DataKi: >1.00E+7nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202401((RR/SS)-2-[1-(4-chlorophenyl)-2-methylpropyl]piper...)
Affinity DataKi: >1.00E+7nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202401((RR/SS)-2-[1-(4-chlorophenyl)-2-methylpropyl]piper...)
Affinity DataIC50:  32nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202401((RR/SS)-2-[1-(4-chlorophenyl)-2-methylpropyl]piper...)
Affinity DataIC50:  51nMAssay Description:Inhibition of [3H]NE uptake into human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202401((RR/SS)-2-[1-(4-chlorophenyl)-2-methylpropyl]piper...)
Affinity DataIC50:  32nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202401((RR/SS)-2-[1-(4-chlorophenyl)-2-methylpropyl]piper...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of [3H]5-HT uptake into human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed