BDBM50202405 (RR/SS)-2-[1-(3,4-dichlorophenyl)-3-methylbutyl]-1-methylpiperidine::(RS/SR)-2-[1-(3,4-dichlorophenyl)-3-methylbutyl]-1-methylpiperidine::CHEMBL387117

SMILES CC(C)CC(C1CCCCN1C)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=FRKGVKAPAMAQSO-UHFFFAOYSA-N

Data  6 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50202405   

TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202405((RR/SS)-2-[1-(3,4-dichlorophenyl)-3-methylbutyl]-1...)
Affinity DataKi:  6.60nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202405((RR/SS)-2-[1-(3,4-dichlorophenyl)-3-methylbutyl]-1...)
Affinity DataKi:  6.60nMAssay Description:Displacement of [125I]RTI-55 from human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202405((RR/SS)-2-[1-(3,4-dichlorophenyl)-3-methylbutyl]-1...)
Affinity DataKi:  190nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202405((RR/SS)-2-[1-(3,4-dichlorophenyl)-3-methylbutyl]-1...)
Affinity DataKi:  190nMAssay Description:Displacement of [125I]RTI-55 from human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202405((RR/SS)-2-[1-(3,4-dichlorophenyl)-3-methylbutyl]-1...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202405((RR/SS)-2-[1-(3,4-dichlorophenyl)-3-methylbutyl]-1...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [125I]RTI-55 from human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202405((RR/SS)-2-[1-(3,4-dichlorophenyl)-3-methylbutyl]-1...)
Affinity DataIC50:  13nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202405((RR/SS)-2-[1-(3,4-dichlorophenyl)-3-methylbutyl]-1...)
Affinity DataIC50:  13nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202405((RR/SS)-2-[1-(3,4-dichlorophenyl)-3-methylbutyl]-1...)
Affinity DataIC50:  28nMAssay Description:Inhibition of [3H]NE uptake into human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202405((RR/SS)-2-[1-(3,4-dichlorophenyl)-3-methylbutyl]-1...)
Affinity DataIC50:  28nMAssay Description:Inhibition of [3H]NE uptake into human NET expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202405((RR/SS)-2-[1-(3,4-dichlorophenyl)-3-methylbutyl]-1...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of [3H]5-HT uptake into human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Human)
Massachusetts College of Pharmacy and Health Sciences

Curated by ChEMBL
LigandPNGBDBM50202405((RR/SS)-2-[1-(3,4-dichlorophenyl)-3-methylbutyl]-1...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of [3H]5-HT uptake into human SERT expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed