BDBM50203166 (2S)-2-methylamino-5-nitroguanidino-pentanoicacid ((3R)-piperidin-3-yl)amide::CHEMBL226499

SMILES CN[C@@H](CCCNC(N)=N[N+]([O-])=O)C(=O)N[C@@H]1CCCNC1

InChI Key InChIKey=GKXXRRBFZPZEMJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50203166   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50203166((2S)-2-methylamino-5-nitroguanidino-pentanoicacid ...)
Affinity DataKi:  2.26E+3nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50203166((2S)-2-methylamino-5-nitroguanidino-pentanoicacid ...)
Affinity DataKi:  1.74E+5nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50203166((2S)-2-methylamino-5-nitroguanidino-pentanoicacid ...)
Affinity DataKi:  2.42E+5nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as nitric oxide production by hemoglobin capture assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed