BDBM50203298 CHEMBL3974845

SMILES Cc1cnc(Nc2ccc(\C=C\C(=O)NO)cc2)nc1-c1cc2ccccc2o1

InChI Key InChIKey=FREGDZUPJZDGER-DHZHZOJOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50203298   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50203298(CHEMBL3974845)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of GST-tagged recombinant human cytoplasmic JAK3 expressed in baculovirus using TK-substrate-biotin as substrate preincubated for 5 mins f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50203298(CHEMBL3974845)
Affinity DataIC50:  226nMAssay Description:Inhibition of GST-tagged recombinant human JAK2 expressed in baculovirus using TK-substrate-biotin as substrate preincubated for 5 mins followed by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed