BDBM50203298 CHEMBL3974845
SMILES Cc1cnc(Nc2ccc(\C=C\C(=O)NO)cc2)nc1-c1cc2ccccc2o1
InChI Key InChIKey=FREGDZUPJZDGER-DHZHZOJOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50203298
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Central China Normal University
Curated by ChEMBL
Central China Normal University
Curated by ChEMBL
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of GST-tagged recombinant human cytoplasmic JAK3 expressed in baculovirus using TK-substrate-biotin as substrate preincubated for 5 mins f...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Central China Normal University
Curated by ChEMBL
Central China Normal University
Curated by ChEMBL
Affinity DataIC50: 226nMAssay Description:Inhibition of GST-tagged recombinant human JAK2 expressed in baculovirus using TK-substrate-biotin as substrate preincubated for 5 mins followed by s...More data for this Ligand-Target Pair