BDBM50203820 4-(6-fluoropyridin-3-yl)-N-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}benzamide::CHEMBL221640

SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(cc2)-c2ccc(F)nc2)CC1

InChI Key InChIKey=XWRCSVSWZWMHPY-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50203820   

TargetD(3) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50203820(4-(6-fluoropyridin-3-yl)-N-{4-[4-(2-methoxyphenyl)...)
Affinity DataKi:  0.450nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50203820(4-(6-fluoropyridin-3-yl)-N-{4-[4-(2-methoxyphenyl)...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]spiperone from human dopamine D2(short) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50203820(4-(6-fluoropyridin-3-yl)-N-{4-[4-(2-methoxyphenyl)...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]spiperone from human dopamine D2(long) expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50203820(4-(6-fluoropyridin-3-yl)-N-{4-[4-(2-methoxyphenyl)...)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Human)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50203820(4-(6-fluoropyridin-3-yl)-N-{4-[4-(2-methoxyphenyl)...)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]spiperone from human dopamine D4.4 expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Pig)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50203820(4-(6-fluoropyridin-3-yl)-N-{4-[4-(2-methoxyphenyl)...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]SCH 23990 from porcine dopamine D1 in porcine striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed