BDBM50204312 CHEMBL3936289

SMILES [H][C@]12CCN(C)[C@]3([H])CCC[C@]([H])([C@@H](Cc4ccccc4)C(=O)C1)[C@@]23[H]

InChI Key InChIKey=HWGSTWOVRDYFSO-VAVNGKDRSA-N

Data  39 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 39 hits for monomerid = 50204312   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M3(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi:  661nMAssay Description:Binding affinity to human M3 receptor expressed in CHO cells measured after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H3 receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi:  814nMAssay Description:Displacement of [3H]alpha-methylhistamine from human H3 receptor expressed in HEK Flp-In cells measured after 90 mins by microbeta scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2C(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi:  1.68E+3nMAssay Description:Displacement of [3H]Mesulergine from human 5-HT2C receptor expressed in Flp-IN HEK cells measured after 90 mins by microbeta scintillation counting m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2B(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi:  1.91E+3nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent dopamine transporter(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi:  2.18E+3nMAssay Description:Displacement of [3H]WIN35428 from human DAT expressed in HEK cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M5(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi:  3.49E+3nMAssay Description:Binding affinity to human M5 receptor expressed in CHO cells measured after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1B adrenergic receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Prazosin from human Alpha1B receptor expressed in HEK-T cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-2B adrenergic receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Rauwolscine from human Alpha2B receptor expressed in HEK-T cells measured after 90 mins by microbeta scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 3A(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]GR65630 from human 5-HT3 receptor expressed in HEK-T cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 5A(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT5A receptor expressed in Flp-In CHO cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(1A) dopamine receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from human D1 receptor expressed in HEK-T cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-2A adrenergic receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Rauwolscine from human Alpha2A receptor expressed in MDCK cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M4(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human M4 receptor expressed in CHO cells measured after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent serotonin transporter(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Citalopram from human SERT expressed in HEK cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H4 receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Histamine from H4 receptor (unknown origin) measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDelta-type opioid receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DADLE from human DOR expressed in HEK cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1A(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Way100635 from human 5-HT1A receptor expressed in CHO cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1E(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]5-HT from human 5-HT1E receptor expressed in HEK cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 6(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in HEK cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1A adrenergic receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Prazosin from human Alpha1A receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-2C adrenergic receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Rauwolscine from human Alpha2C receptor expressed in MDCK cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(3) dopamine receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from D3 receptor (unknown origin) expressed in HEK-T cells measured after 90 mins by microbeta scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(4) dopamine receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D4 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(1B) dopamine receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH23390 from human D5 receptor expressed in HEK-T cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H1 receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Pyrilamine from human H1 receptor expressed in HEK cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium-dependent noradrenaline transporter(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Nisoxetine from human NET expressed in HEK cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMu-type opioid receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK cells after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 7(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]LSD from human 5-HT7 receptor expressed in HEK cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKappa-type opioid receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]U69593 from KOR (unknown origin) expressed in HEKT cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1B(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]5-CT from human 5-HT1B receptor expressed in HEK cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 2A(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Ketanserin from 5-HT2A receptor (unknown origin) measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-2 adrenergic receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CGP12177 from human beta2 receptor expressed in HEK Flp-In cells measured after 90 mins by microbeta scintillation counting metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAlpha-1D adrenergic receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]Prazosin from human Alpha1D receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M1(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human M1 receptor expressed in CHO cells measured after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 1D(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]5-CT from human 5-HT1D receptor expressed in HEK-T cells measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetD(2) dopamine receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in fibroblast cells measured after 90 mins by microbeta scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistamine H2 receptor(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to H2 receptor (unknown origin) expressed in HEKT cells measured after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMuscarinic acetylcholine receptor M2(Human)
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50204312(CHEMBL3936289)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human M2 receptor expressed in CHO cells measured after 90 mins by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed