BDBM50205637 CHEMBL3896239

SMILES CC1CN(CC2CC2)c2cc(cc(C(=O)NCc3c(C)cc(C)[nH]c3=O)c12)-c1ccc(CN2CCOCC2)cc1

InChI Key InChIKey=PYGGXHPKSYBVSY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50205637   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50205637(CHEMBL3896239)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of human wild type EZH2 using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHistone-lysine N-methyltransferase EZH2(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50205637(CHEMBL3896239)
Affinity DataIC50:  1.52E+4nMAssay Description:Inhibition of human wild type EZH2 using histone H3 as substrate after 1 hr in presence of 3H-SAM by filter paper detection analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed