BDBM50206249 CHEMBL3900048

SMILES Clc1ccc2c(NC3=NC4(CO3)CN3CCC4CC3)ncnn12

InChI Key InChIKey=XTBJFQBZMIIWEY-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206249   

Target5-hydroxytryptamine receptor 3A(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206249BDBM50206249(CHEMBL3900048)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) expressed in HEK293 cells assessed as inhibition of Ca2+ flux by Fluo-4-AM dye based FLIPR as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2018
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206249BDBM50206249(CHEMBL3900048)
Affinity DataEC50:  5.60E+3nMAssay Description:Agonist activity at alpha7 nACh receptor (unknown origin) expressed in HEK293 cells assessed as increase in Ca2+ flux by Fluo-4-AM dye based FLIPR as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2018
Entry Details Article
PubMed