BDBM50206276 5-chloro-N-(4-(2-(4-ethylpiperazin-1-yl)ethyl)phenyl)-4-(1H-indol-6-yl)pyrimidin-2-amine::CHEMBL398989

SMILES CCN1CCN(CCc2ccc(Nc3ncc(Cl)c(n3)-c3ccc4cc[nH]c4c3)cc2)CC1

InChI Key InChIKey=LSPQVYOMPRTETO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206276   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206276(5-chloro-N-(4-(2-(4-ethylpiperazin-1-yl)ethyl)phen...)
Affinity DataIC50: 37nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206276(5-chloro-N-(4-(2-(4-ethylpiperazin-1-yl)ethyl)phen...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed