BDBM50206283 2-(4-(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloropyrimidin-2-ylamino)phenyl)ethanol::CHEMBL233205

SMILES CC(C)(N)c1ccc(cc1)-c1nc(Nc2ccc(CCO)cc2)ncc1Cl

InChI Key InChIKey=PLRCXTHWEOUWPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206283   

TargetVascular endothelial growth factor receptor 2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206283(2-(4-(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloropyr...)
Affinity DataIC50: 69nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50206283(2-(4-(4-(4-(2-aminopropan-2-yl)phenyl)-5-chloropyr...)
Affinity DataIC50: 687nMAssay Description:Inhibition of CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed