BDBM50206393 CHEMBL3954695

SMILES O=C(O)/C=C\C(=O)Nc1cccc(-c2n[nH]c3ccc(NS(=O)(=O)c4ccc([N+](=O)[O-])cc4)cc23)c1

InChI Key InChIKey=MGHRIOSQJVOCSQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50206393   

TargetAurora kinase B(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206393BDBM50206393(CHEMBL3954695)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant full-length His-tagged Aurora B expressed in baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Taiwan National Health Research Institutes

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206393BDBM50206393(CHEMBL3954695)
Affinity DataIC50: 480nMAssay Description:Inhibition of GST-tagged Aurora A (123 to 401 residues) (unknown origin) preincubated for 15 mins followed by tetra(LRRWSLG) substrate addition measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2018
Entry Details Article
PubMed