BDBM50206421 3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)isoxazole::4-(3-(4-fluorophenyl)-5-isopropylisoxazol-4-yl)pyridine::4-[3-(4-fluorophenyl)-5-isopropylisoxazol-4-yl]pyridine::CHEMBL220227

SMILES CC(C)c1onc(c1-c1ccncc1)-c1ccc(F)cc1

InChI Key InChIKey=BOCQIRYQTWRJMD-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50206421   

TargetMitogen-activated protein kinase 10(Human)
Eberhard-Karls-University TüBingen

Curated by ChEMBL
LigandPNGBDBM50206421(3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)iso...)
Affinity DataIC50:  540nMAssay Description:Inhibition of JNK3 by non-radioactive immunosorbent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University TüBingen

Curated by ChEMBL
LigandPNGBDBM50206421(3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)iso...)
Affinity DataIC50:  450nMAssay Description:Inhibition of p38alpha MAPK by non-radioactive immunosorbent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University TüBingen

Curated by ChEMBL
LigandPNGBDBM50206421(3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)iso...)
Affinity DataIC50:  450nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 9(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50206421(3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)iso...)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCasein kinase I isoform delta(Rat)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50206421(3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)iso...)
Affinity DataIC50:  230nMAssay Description:Inhibition of GST-fused rat CK1delta by Cherenkov counting in presence of 20 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 14(Human)
Eberhard-Karls-University TüBingen

Curated by ChEMBL
LigandPNGBDBM50206421(3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)iso...)
Affinity DataIC50:  450nMAssay Description:Inhibition of p38alpha by Cherenkov countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCasein kinase I isoform delta(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50206421(3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)iso...)
Affinity DataIC50:  230nMAssay Description:Inhibition of CK1delta by Cherenkov counting in presence of 20 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 9(Human)
Eberhard-Karls University

Curated by ChEMBL
LigandPNGBDBM50206421(3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)iso...)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of JNK2 by Cherenkov counting in presence of 20 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Eberhard-Karls-University TüBingen

Curated by ChEMBL
LigandPNGBDBM50206421(3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)iso...)
Affinity DataIC50:  540nMAssay Description:Inhibition of JNK3 by Cherenkov counting in presence of 20 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMitogen-activated protein kinase 10(Human)
Eberhard-Karls-University TüBingen

Curated by ChEMBL
LigandPNGBDBM50206421(3-(4-fluorophenyl)-5-isopropyl-4-(pyridin-4-yl)iso...)
Affinity DataIC50:  540nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed