BDBM50206500 CHEMBL241166::N2-octanoyl-9-(2'-O-octanoyl-beta-D-arabinofuranosyl)guanine

SMILES CCCCCCCC(=O)Nc1nc2c(ncn2[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2OC(=O)CCCCCCC)c(=O)[nH]1

InChI Key InChIKey=YACNZCYULMFHME-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50206500   

TargetThymidine kinase(HHV-3)
University of Ferrara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206500BDBM50206500(N2-octanoyl-9-(2'-O-octanoyl-beta-D-arabinofuranos...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of VZV TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase, cytosolic(Human)
University of Ferrara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206500BDBM50206500(N2-octanoyl-9-(2'-O-octanoyl-beta-D-arabinofuranos...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human TK1 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
University of Ferrara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206500BDBM50206500(N2-octanoyl-9-(2'-O-octanoyl-beta-D-arabinofuranos...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of HSV1 TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetDiacylglycerol kinase 1(Fruit fly)
University of Ferrara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206500BDBM50206500(N2-octanoyl-9-(2'-O-octanoyl-beta-D-arabinofuranos...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of Drosophila melanogaster dGK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
University of Ferrara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206500BDBM50206500(N2-octanoyl-9-(2'-O-octanoyl-beta-D-arabinofuranos...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of Drosophila melanogaster dNK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase 2, mitochondrial(Human)
University of Ferrara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206500BDBM50206500(N2-octanoyl-9-(2'-O-octanoyl-beta-D-arabinofuranos...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed