BDBM50206508 1-(2'-O-phenylacetyl-beta-D-arabinofuranosyl)-5(E)-(2-bromovinyl)uracil::CHEMBL241407

SMILES O=C(Cc1ccccc1)O[C@H]1[C@H](O)[C@@H](CO)O[C@H]1n1cc(C=CBr)c(=O)[nH]c1=O

InChI Key InChIKey=FMVGLLPOZGDPTQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50206508   

TargetThymidine kinase 2, mitochondrial(Human)
University of Ferrara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206508BDBM50206508(1-(2'-O-phenylacetyl-beta-D-arabinofuranosyl)-5(E)...)
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of human TK2 assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase(HHV-1)
University of Ferrara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206508BDBM50206508(1-(2'-O-phenylacetyl-beta-D-arabinofuranosyl)-5(E)...)
Affinity DataIC50: 2.47E+5nMAssay Description:Inhibition of HSV1 TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetThymidine kinase(HHV-3)
University of Ferrara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206508BDBM50206508(1-(2'-O-phenylacetyl-beta-D-arabinofuranosyl)-5(E)...)
Affinity DataIC50: 2.68E+5nMAssay Description:Inhibition of VZV TK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed
TargetDeoxynucleoside kinase(Fruit fly)
University of Ferrara

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50206508BDBM50206508(1-(2'-O-phenylacetyl-beta-D-arabinofuranosyl)-5(E)...)
Affinity DataIC50: 4.19E+5nMAssay Description:Inhibition of Drosophila melanogaster dNK assessed as [methyl-3H]dThd phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMed