BDBM50207862 3-isopropyl-N-(3-(3-(2-(methylamino)pyridin-4-yl)pyridin-2-yloxy)phenyl)benzamide::CHEMBL246150

SMILES CNc1cc(ccn1)-c1cccnc1Oc1cccc(NC(=O)c2cccc(c2)C(C)C)c1

InChI Key InChIKey=FODDHYRWTNFLQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207862   

TargetAngiopoietin-1 receptor(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50207862(3-isopropyl-N-(3-(3-(2-(methylamino)pyridin-4-yl)p...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Tie2 after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50207862(3-isopropyl-N-(3-(3-(2-(methylamino)pyridin-4-yl)p...)
Affinity DataIC50: 18nMAssay Description:Inhibition of KDR after 90 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed