BDBM50207890 1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-(4-pyridin-4-yl-benzyl)-1,3,8-triaza-spiro[4.5]decane-2,4-dione::CHEMBL266738

SMILES COc1cccc(c1)N1C(=O)N(Cc2ccccc2F)C2(CCN(Cc3ccc(cc3)-c3ccncc3)CC2)C1=O

InChI Key InChIKey=FLYSTSPNPXBSFJ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50207890   

TargetMelanin-concentrating hormone receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207890(1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-(4-pyri...)
Affinity DataKi:  44nMAssay Description:Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50207890(1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-(4-pyri...)
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed