BDBM50208494 2-(4-(6-morpholino-4-oxo-4H-pyran-2-yl)benzyl)isoindoline-1,3-dione::CHEMBL374290

SMILES O=C1N(Cc2ccc(cc2)-c2cc(=O)cc(o2)N2CCOCC2)C(=O)c2ccccc12

InChI Key InChIKey=PRXXSUSEEXXFEB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50208494   

TargetDNA-dependent protein kinase catalytic subunit(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50208494(2-(4-(6-morpholino-4-oxo-4H-pyran-2-yl)benzyl)isoi...)
Affinity DataIC50: 500nMAssay Description:Inhibition of DNA-PK in HeLa cell nuclear extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine-protein kinase ATM(Human)
Newcastle University

Curated by ChEMBL
LigandPNGBDBM50208494(2-(4-(6-morpholino-4-oxo-4H-pyran-2-yl)benzyl)isoi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ATM kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed