BDBM50208750 1-{2-fluoro-4-[(5-sulfamoyl-1,3,4-thiadiazol-2-yl)sulfamoyl]phenyl}-3-{[(1R,2S,6S,9R)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.0^{2,6}]dodecan-6-yl]methyl}thiourea::CHEMBL395981

SMILES CC1(C)O[C@@H]2CO[C@@]3(CNC(=S)Nc4ccc(cc4F)S(=O)(=O)Nc4nnc(s4)S(N)(=O)=O)OC(C)(C)O[C@H]3[C@@H]2O1

InChI Key InChIKey=BTMYCYUSKNWPJE-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50208750   

TargetCarbonic anhydrase 2(Human)
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50208750(1-{2-fluoro-4-[(5-sulfamoyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataKi:  9nMAssay Description:Inhibition of human recombinant CA2 after 15 mins by CO2 hydration stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50208750(1-{2-fluoro-4-[(5-sulfamoyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataKi:  21nMAssay Description:Inhibition of human recombinant CA14 after 15 mins by CO2 hydration stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50208750(1-{2-fluoro-4-[(5-sulfamoyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant CA7 after 15 mins by CO2 hydration stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50208750(1-{2-fluoro-4-[(5-sulfamoyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataKi:  76nMAssay Description:Inhibition of human recombinant CA9 after 15 mins by CO2 hydration stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50208750(1-{2-fluoro-4-[(5-sulfamoyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataKi:  850nMAssay Description:Inhibition of human recombinant CA5A after 15 mins by CO2 hydration stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50208750(1-{2-fluoro-4-[(5-sulfamoyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataKi:  9.40E+3nMAssay Description:Inhibition of human recombinant CA1 after 15 mins by CO2 hydration stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Ecole Nationale Sup£Rieure De Chimie De Montpellier

Curated by ChEMBL
LigandPNGBDBM50208750(1-{2-fluoro-4-[(5-sulfamoyl-1,3,4-thiadiazol-2-yl)...)
Affinity DataKi:  8.93E+4nMAssay Description:Inhibition of human recombinant CA4 after 15 mins by CO2 hydration stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMed