BDBM50209382 2-(4-{[2-(3-chlorophenyl)-2-hydroxyethyl]amino}-2-oxo-1,2-dihydropyridin-3-yl)-N,4-dimethyl-1H-1,3-benzodiazole-6-carboximidamide::CHEMBL425819

SMILES CNC(=N)c1cc(C)c2nc([nH]c2c1)-c1c(NCC(O)c2cccc(Cl)c2)cc[nH]c1=O

InChI Key InChIKey=WGPYWDLNUPWWNN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50209382   

TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209382(2-(4-{[2-(3-chlorophenyl)-2-hydroxyethyl]amino}-2-...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of CYP1A2 in microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209382(2-(4-{[2-(3-chlorophenyl)-2-hydroxyethyl]amino}-2-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209382(2-(4-{[2-(3-chlorophenyl)-2-hydroxyethyl]amino}-2-...)
Affinity DataIC50:  7.60E+4nMAssay Description:Inhibition of CYP2C9 in microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209382(2-(4-{[2-(3-chlorophenyl)-2-hydroxyethyl]amino}-2-...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of CYP3A4 in microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed