BDBM50209510 (S) N-(2-((1-(3,4-dimethoxyphenethyl)pyrrolidin-2-yl)methylcarbamoyl)phenyl)quinoline-3-carboxamide::CHEMBL397418

SMILES COc1ccc(CCN2CCC[C@H]2CNC(=O)c2ccccc2NC(=O)c2cnc3ccccc3c2)cc1OC

InChI Key InChIKey=MRHYRUNEBSENJS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50209510   

TargetATP-dependent translocase ABCB1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50209510((S) N-(2-((1-(3,4-dimethoxyphenethyl)pyrrolidin-2-...)
Affinity DataEC50:  329nMAssay Description:Reversal of P-gp-mediated multidrug resistance to vinblastine in human CEM/VLB500 cells after 3 days by resazurin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed