BDBM50209670 17-(cyclopropylmethyl)morphinan-3-yl(5alpha)-17-(cyclopropylmethyl)-14-hydroxy-6-oxo-4,5-epoxymorphiana-3-yl sebacoylate::CHEMBL224014

SMILES O[C@]12CCC(=O)[C@@H]3Oc4c5c(C[C@H]1N(CC1CC1)CC[C@@]235)ccc4OC(=O)CCCCCCCCC(=O)Oc1ccc2C[C@@H]3C4CCCC[C@]4(CCN3CC3CCC3)c2c1

InChI Key InChIKey=VOTCBKOYCAMWBJ-CELWHGEPSA-N

Data  3 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50209670   

TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50209670(17-(cyclopropylmethyl)morphinan-3-yl(5alpha)-17-(c...)
Affinity DataKi:  0.120nMAssay Description:Displacement of [3H]U-69593 from human opioid kappa receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50209670(17-(cyclopropylmethyl)morphinan-3-yl(5alpha)-17-(c...)
Affinity DataKi:  0.290nMAssay Description:Agonist activity at human opioid gamma receptor expressed in CHO cells assessed as inhibition of DAGO-stimulated [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50209670(17-(cyclopropylmethyl)morphinan-3-yl(5alpha)-17-(c...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]naltrindole from human opioid delta receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50209670(17-(cyclopropylmethyl)morphinan-3-yl(5alpha)-17-(c...)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at human opioid kappa receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50209670(17-(cyclopropylmethyl)morphinan-3-yl(5alpha)-17-(c...)
Affinity DataIC50:  160nMAssay Description:Agonist activity at human opioid gamma receptor expressed in CHO cells assessed as inhibition of DAGO-stimulated [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50209670(17-(cyclopropylmethyl)morphinan-3-yl(5alpha)-17-(c...)
Affinity DataEC50:  4.40nMAssay Description:Agonist activity at human opioid gamma receptor expressed in CHO cells assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed