BDBM50210225 1-(2-(1-(bis(2-chlorophenyl)methyl)-4-hydroxypiperidin-4-yl)benzyl)-3-ethylurea::CHEMBL232074

SMILES CCNC(=O)NCc1ccccc1C1(O)CCN(CC1)C(c1ccccc1Cl)c1ccccc1Cl

InChI Key InChIKey=PEWJLCPHBNRFOD-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210225   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210225(1-(2-(1-(bis(2-chlorophenyl)methyl)-4-hydroxypiper...)
Affinity DataKi:  12nMAssay Description:Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210225(1-(2-(1-(bis(2-chlorophenyl)methyl)-4-hydroxypiper...)
Affinity DataKi:  304nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210225(1-(2-(1-(bis(2-chlorophenyl)methyl)-4-hydroxypiper...)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210225(1-(2-(1-(bis(2-chlorophenyl)methyl)-4-hydroxypiper...)
Affinity DataKi:  2.45E+3nMAssay Description:Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed