BDBM50210240 1-(bis(2-chlorophenyl)methyl)-4-(2-((4-methylpiperazin-1-yl)methyl)phenyl)piperidin-4-ol::CHEMBL232076

SMILES CN1CCN(Cc2ccccc2C2(O)CCN(CC2)C(c2ccccc2Cl)c2ccccc2Cl)CC1

InChI Key InChIKey=DMOYSEGTQIGQTM-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210240   

TargetNociceptin receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210240(1-(bis(2-chlorophenyl)methyl)-4-(2-((4-methylpiper...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [125I][Tyr14]nociceptin FQ from human NOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210240(1-(bis(2-chlorophenyl)methyl)-4-(2-((4-methylpiper...)
Affinity DataKi:  139nMAssay Description:Displacement of [3H]diprenorphine from human KOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210240(1-(bis(2-chlorophenyl)methyl)-4-(2-((4-methylpiper...)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50210240(1-(bis(2-chlorophenyl)methyl)-4-(2-((4-methylpiper...)
Affinity DataKi:  1.71E+3nMAssay Description:Displacement of [3H]diprenorphine from human DOP receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed