BDBM50210534 (S)-methyl 2-(2-((S)-2,6-dioxo-3-(3,4,5-trimethoxybenzamido)piperidin-1-yl)acetamido)-5-(3-nitroguanidino)pentanoate::CHEMBL246780

SMILES COC(=O)[C@H](CCCNC(N)=N[N+]([O-])=O)NC(=O)CN1C(=O)CC[C@H](NC(=O)c2cc(OC)c(OC)c(OC)c2)C1=O

InChI Key InChIKey=TYVSUIISWMVVPD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50210534   

Target72 kDa type IV collagenase(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50210534((S)-methyl 2-(2-((S)-2,6-dioxo-3-(3,4,5-trimethoxy...)
Affinity DataIC50: 300nMAssay Description:Inhibition of MMP2 after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50210534((S)-methyl 2-(2-((S)-2,6-dioxo-3-(3,4,5-trimethoxy...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of pig kidney microsomal aminopeptidase assessed as liberation of p-nitroanilideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50210534((S)-methyl 2-(2-((S)-2,6-dioxo-3-(3,4,5-trimethoxy...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of pig kidney microsomes aminopeptidase N preincubated for 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed