BDBM50210992 (R,E)-3-(2-(3-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-3-oxoprop-1-enyl)-5-chlorophenylamino)-4-aminocyclobut-3-ene-1,2-dione::CHEMBL389293

SMILES C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)\C=C\c1ccc(Cl)cc1Nc1c(N)c(=O)c1=O

InChI Key InChIKey=CDFCCOBGVDQLRB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50210992   

TargetC-C chemokine receptor type 1(Human)
Tanabe Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210992((R,E)-3-(2-(3-(4-(4-fluorobenzyl)-2-methylpiperazi...)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at human CCR1 expressed in THP1 cells assessed as effect on MIP-1-alpha-induced calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 1(Human)
Tanabe Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50210992((R,E)-3-(2-(3-(4-(4-fluorobenzyl)-2-methylpiperazi...)
Affinity DataIC50: 7nMAssay Description:Displacement of [125I]MIP1-alpha from human CCR1 expressed in THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed