BDBM50211023 CHEMBL245061::methyl 2-(3,4-dichlorophenyl)cyclopent-1-enecarboxylate

SMILES COC(=O)C1=C(CCC1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=ZKDZVMXERDGTGV-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50211023   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211023(CHEMBL245061 | methyl 2-(3,4-dichlorophenyl)cyclop...)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [125I]RTI55 from human DAT transfected in COS1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211023(CHEMBL245061 | methyl 2-(3,4-dichlorophenyl)cyclop...)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211023(CHEMBL245061 | methyl 2-(3,4-dichlorophenyl)cyclop...)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of [3H]DA uptake in human DAT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211023(CHEMBL245061 | methyl 2-(3,4-dichlorophenyl)cyclop...)
Affinity DataKi:  1.10E+4nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211023(CHEMBL245061 | methyl 2-(3,4-dichlorophenyl)cyclop...)
Affinity DataKi:  1.10E+4nMAssay Description:Displacement of [125I]RTI55 from human NET transfected in COS1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211023(CHEMBL245061 | methyl 2-(3,4-dichlorophenyl)cyclop...)
Affinity DataKi:  2.80E+4nMAssay Description:Inhibition of [3H]DA uptake in human NET expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211023(CHEMBL245061 | methyl 2-(3,4-dichlorophenyl)cyclop...)
Affinity DataKi:  7.85E+5nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in COS1 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
University Of Aarhus

Curated by ChEMBL
LigandPNGBDBM50211023(CHEMBL245061 | methyl 2-(3,4-dichlorophenyl)cyclop...)
Affinity DataKi:  7.90E+5nMAssay Description:Displacement of [125I]RTI55 from human SERT transfected in COS1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed