BDBM50211069 CHEMBL3952384

SMILES Cl.NC1=NC2(CCSCC2)N(OCCCOc2ccc(Br)cc2)C(N)=N1

InChI Key InChIKey=QLWAWGZCCPSUGU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50211069   

TargetDihydrofolate reductase(Homo sapiens (Human))
Shanghai Institute Of Pharmaceutical Industry

Curated by ChEMBL
LigandPNGBDBM50211069(CHEMBL3952384)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of recombinant human DHFR using DHF as substrate measured every 5 sec over 6 mins in presence of NADPH by UV-Visible spectrophotometric me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed