BDBM50211302 5a,10c-Dihydro-2H-dibenzo[cd,g]indazol-6-one::CHEMBL252761

SMILES Oc1c2cccc3[nH][nH]c(c23)c2ccccc12

InChI Key InChIKey=BRKXAADNUXOTJZ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50211302   

TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50211302(5a,10c-Dihydro-2H-dibenzo[cd,g]indazol-6-one | CHE...)
Affinity DataIC50: 40nMAssay Description:Inhibition of JNK1 (unknown origin) by ATP-competitive assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50211302(5a,10c-Dihydro-2H-dibenzo[cd,g]indazol-6-one | CHE...)
Affinity DataIC50: 40nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50211302(5a,10c-Dihydro-2H-dibenzo[cd,g]indazol-6-one | CHE...)
Affinity DataIC50: 40nMAssay Description:Inhibition of JNK2 (unknown origin) by ATP-competitive assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50211302(5a,10c-Dihydro-2H-dibenzo[cd,g]indazol-6-one | CHE...)
Affinity DataIC50: 40nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50211302(5a,10c-Dihydro-2H-dibenzo[cd,g]indazol-6-one | CHE...)
Affinity DataIC50: 42nMAssay Description:Inhibition of JNK1 (unknown origin) using ULight-4E-BP1 peptide as substrate incubated for 90 mins in presence of ATP by Lance ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50211302(5a,10c-Dihydro-2H-dibenzo[cd,g]indazol-6-one | CHE...)
Affinity DataIC50: 87nMAssay Description:Inhibition of JNK3 (unknown origin) using ULight-4E-BP1 peptide as substrate incubated for 90 mins in presence of ATP by Lance ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50211302(5a,10c-Dihydro-2H-dibenzo[cd,g]indazol-6-one | CHE...)
Affinity DataIC50: 90nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50211302(5a,10c-Dihydro-2H-dibenzo[cd,g]indazol-6-one | CHE...)
Affinity DataIC50: 90nMAssay Description:Inhibition of JNK3 (unknown origin) by ATP-competitive assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 10(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50211302(5a,10c-Dihydro-2H-dibenzo[cd,g]indazol-6-one | CHE...)
Affinity DataIC50: 190nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed