BDBM50211445 4-(4-(1H-indol-3-yl)-5-methylpyrimidin-2-ylamino)-N-ethylpiperidine-1-carboxamide::CHEMBL245724

SMILES CCNC(=O)N1CCC(CC1)Nc1ncc(C)c(n1)-c1c[nH]c2ccccc12

InChI Key InChIKey=UGZLJUFPCPHHSW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211445   

TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211445(4-(4-(1H-indol-3-yl)-5-methylpyrimidin-2-ylamino)-...)
Affinity DataIC50: 250nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211445(4-(4-(1H-indol-3-yl)-5-methylpyrimidin-2-ylamino)-...)
Affinity DataIC50: 320nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211445(4-(4-(1H-indol-3-yl)-5-methylpyrimidin-2-ylamino)-...)
Affinity DataIC50: 410nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranscription factor Jun(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211445(4-(4-(1H-indol-3-yl)-5-methylpyrimidin-2-ylamino)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cJun translocation in IL-1-beta-stimulated A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed