BDBM50211447 2-((S)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-ylamino)piperidin-1-yl)-N-methylacetamide::CHEMBL245334

SMILES CNC(=O)CN1CCC[C@@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12

InChI Key InChIKey=JMOMBPSAYLGZAN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211447   

TargetMitogen-activated protein kinase 8(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211447(2-((S)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl...)
Affinity DataIC50: 139nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211447(2-((S)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl...)
Affinity DataIC50: 267nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211447(2-((S)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2 by IMAP technologyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTranscription factor Jun(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50211447(2-((S)-3-(5-chloro-4-(1H-indol-3-yl)pyrimidin-2-yl...)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of cJun translocation in IL-1-beta-stimulated A549 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed