BDBM50211486 4-methyl-[1,2,3]thiadiazole-5-carboxylic acid (3,5a,10-trimethyl-2-oxo-2,3,3a,4,5,5a,6,10,10a,10b-decahydro-1-oxa-7-thia-9-aza-dicyclopenta[a,g]naphthalen-8-yl)-amide::CHEMBL375910

SMILES Cc1nnsc1C(=O)Nc1nc2c(s1)CC1(C)CCC3C(C)C(=O)OC3C1C2C

InChI Key InChIKey=XLAGJGYXKBDIQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50211486   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211486BDBM50211486(4-methyl-[1,2,3]thiadiazole-5-carboxylic acid (3,5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Johann Wolfgang Goethe-UniversitäT

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211486BDBM50211486(4-methyl-[1,2,3]thiadiazole-5-carboxylic acid (3,5...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed