BDBM50211589 CHEMBL3898548

SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccc(Br)cc1

InChI Key InChIKey=QLUSYRMWCOICRS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211589   

TargetCarbonic anhydrase 7(Human)
Abant Izzet Baysal University

Curated by ChEMBL
LigandPNGBDBM50211589(CHEMBL3898548)
Affinity DataKi:  7.40nMAssay Description:Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Abant Izzet Baysal University

Curated by ChEMBL
LigandPNGBDBM50211589(CHEMBL3898548)
Affinity DataKi:  8.60nMAssay Description:Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Abant Izzet Baysal University

Curated by ChEMBL
LigandPNGBDBM50211589(CHEMBL3898548)
Affinity DataKi:  286nMAssay Description:Inhibition of recombinant human carbonic anhydrase 4 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Abant Izzet Baysal University

Curated by ChEMBL
LigandPNGBDBM50211589(CHEMBL3898548)
Affinity DataKi:  775nMAssay Description:Inhibition of recombinant human carbonic anhydrase 1 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/12/2018
Entry Details Article
PubMed