BDBM50211740 (1R)-phenyl-[(1R,2S,7S,8S,9S)-3,3,7-trimethyltricyclo[5.4.0.02,9]undec-8-yl]methanol::CHEMBL376840

SMILES CC1(C)CCC[C@]2(C)[C@@H]([C@@H](O)c3ccccc3)[C@H]3CC[C@@H]2[C@H]31

InChI Key InChIKey=FGZVLGOUUPQOAB-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50211740   

TargetUDP-glucuronosyltransferase 2B7(Human)
University of Helsinki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211740BDBM50211740((1R)-phenyl-[(1R,2S,7S,8S,9S)-3,3,7-trimethyltricy...)
Affinity DataKi:  18.4nMAssay Description:Inhibition of human UGT2B7 assessed as reduction of estriol glucuronidationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 2B7(Human)
University of Helsinki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211740BDBM50211740((1R)-phenyl-[(1R,2S,7S,8S,9S)-3,3,7-trimethyltricy...)
Affinity DataIC50: 47nMAssay Description:Inhibition of human UGT2B7 by substrate-independent inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 2B7(Human)
University of Helsinki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211740BDBM50211740((1R)-phenyl-[(1R,2S,7S,8S,9S)-3,3,7-trimethyltricy...)
Affinity DataIC50: 54nMAssay Description:Inhibition of human UGT2B7 assessed as reduction of estriol glucuronidationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetUDP-glucuronosyltransferase 2B17(Human)
University of Helsinki

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50211740BDBM50211740((1R)-phenyl-[(1R,2S,7S,8S,9S)-3,3,7-trimethyltricy...)
Affinity DataKi:  2.18E+4nMAssay Description:Inhibition of human recombinant UGT2B17 assessed as reduction of scopoletin glucuronidationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed