BDBM50212295 (1S,13R,14R)-24-methyl-4,24-diazahexacyclo[12.7.3.0^{1,13}.0^{3,11}.0^{5,10}.0^{16,21}]tetracosa-3(11),5(10),6,8,16(21),17,19-heptaen-19-ol::CHEMBL226114

SMILES CN1CC[C@]23Cc4[nH]c5ccccc5c4C[C@H]2[C@H]1Cc1ccc(O)cc31

InChI Key InChIKey=SGSVRERBPLEULM-UHFFFAOYSA-N

Data  3 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50212295   

TargetDelta-type opioid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50212295((1S,13R,14R)-24-methyl-4,24-diazahexacyclo[12.7.3....)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50212295((1S,13R,14R)-24-methyl-4,24-diazahexacyclo[12.7.3....)
Affinity DataEC50:  0.470nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO membrane assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50212295((1S,13R,14R)-24-methyl-4,24-diazahexacyclo[12.7.3....)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at human delta opioid receptor expressed in CHO membrane assessed as inhibition of SNC80-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50212295((1S,13R,14R)-24-methyl-4,24-diazahexacyclo[12.7.3....)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]U-69593 from human kappa opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50212295((1S,13R,14R)-24-methyl-4,24-diazahexacyclo[12.7.3....)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed