BDBM50212696 2-(7-(2-(4-(trifluoromethyl)benzyloxy)benzylthio)-2,3-dihydro-1H-inden-4-yloxy)acetic acid::CHEMBL234665

SMILES OC(=O)COc1ccc(SCc2ccccc2OCc2ccc(cc2)C(F)(F)F)c2CCCc12

InChI Key InChIKey=UQDCLZWSSZJCMF-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50212696   

LigandPNGBDBM50212696(2-(7-(2-(4-(trifluoromethyl)benzyloxy)benzylthio)-...)
Affinity DataIC50: 10.4nMAssay Description:Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50212696(2-(7-(2-(4-(trifluoromethyl)benzyloxy)benzylthio)-...)
Affinity DataEC50:  230nMAssay Description:Agonist activity at human PPARdelta expressed in HepG2 cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50212696(2-(7-(2-(4-(trifluoromethyl)benzyloxy)benzylthio)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]2-(4-(2-(3-(2,4-difluorophenyl)-1-heptylureido)ethyl)phenoxy)-2-methylbutanoic acid from human PPARalpha after 30 mins by SPA ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50212696(2-(7-(2-(4-(trifluoromethyl)benzyloxy)benzylthio)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]5-(4-(3-(5-methyl-2-phenyloxazol-4-yl)propanoyl)benzyl)thiazolidine-2,4-dione from human PPARgamma after 2 hrs by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed