BDBM50212711 2-(7-(4-(4-fluoro-2-(trifluoromethyl)benzyloxy)benzylthio)-2,3-dihydro-1H-inden-4-yloxy)acetic acid::CHEMBL392950

SMILES OC(=O)COc1ccc(SCc2ccc(OCc3ccc(F)cc3C(F)(F)F)cc2)c2CCCc12

InChI Key InChIKey=PIWIBUHURPMRHK-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50212711   

LigandPNGBDBM50212711(2-(7-(4-(4-fluoro-2-(trifluoromethyl)benzyloxy)ben...)
Affinity DataIC50: 356nMAssay Description:Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50212711(2-(7-(4-(4-fluoro-2-(trifluoromethyl)benzyloxy)ben...)
Affinity DataEC50:  1.72E+3nMAssay Description:Agonist activity at human PPARdelta expressed in HepG2 cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50212711(2-(7-(4-(4-fluoro-2-(trifluoromethyl)benzyloxy)ben...)
Affinity DataIC50: 3.48E+3nMAssay Description:Displacement of [3H]2-(4-(2-(3-(2,4-difluorophenyl)-1-heptylureido)ethyl)phenoxy)-2-methylbutanoic acid from human PPARalpha after 30 mins by SPA ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed