BDBM50212745 (E)-1-(4-((5,6-dimethoxy-2-oxoindolin-3-ylidene)methyl)phenyl)-3-phenylurea::CHEMBL246685

SMILES COc1cc2NC(=O)\C(=C\c3ccc(NC(=O)Nc4ccccc4)cc3)c2cc1OC

InChI Key InChIKey=NWJKFFFSFYKXFX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50212745   

LigandPNGBDBM50212745((E)-1-(4-((5,6-dimethoxy-2-oxoindolin-3-ylidene)me...)
Affinity DataIC50: 200nMAssay Description:Inhibition of RET in mouse NIH3T3MEN2A cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed