BDBM50212816 9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydropyrimido[1,2-a]purine-2,4(1H,3H)-dione::CHEMBL241618

SMILES Cn1c2nc3N(Cc4cccc(Cl)c4)CCCn3c2c(=O)n(C)c1=O

InChI Key InChIKey=DBKCMQYLIZAYNU-UHFFFAOYSA-N

Data  14 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50212816   

TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50212816(9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydro...)
Affinity DataKi:  432nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50212816(9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydro...)
Affinity DataKi:  432nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50212816(9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydro...)
Affinity DataKi:  802nMAssay Description:Displacement of [3H]CCPA from rat adenosine A2a receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50212816(9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydro...)
Affinity DataKi:  802nMAssay Description:Displacement of [3H]MSX-2 from adenosine A2A receptor in rat brain striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2b(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50212816(9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydro...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PSB603 from recombinant human adenosine A2b receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2b(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50212816(9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydro...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]PSB-603 from human adenosine A2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50212816(9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydro...)
Affinity DataKi:  1.12E+3nMAssay Description:Displacement of [3H]MSX2 from adenosine A2A receptor in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Rat)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50212816(9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydro...)
Affinity DataKi:  1.42E+3nMAssay Description:Displacement of [3H]CCPA from adenosine A1 receptor in rat brain cortical membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50212816(9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydro...)
Affinity DataKi:  2.03E+3nMAssay Description:Displacement of [3H]MSX2 from recombinant human adenosine A2a receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2a(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50212816(9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydro...)
Affinity DataKi:  2.03E+3nMAssay Description:Displacement of [3H]MSX-2 from human adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50212816(9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydro...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CCPA from human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A1(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50212816(9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydro...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CCPA from recombinant human adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A3(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50212816(9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydro...)
Affinity DataKi:  1.52E+4nMAssay Description:Displacement of [3H]PSB-11 from human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A3(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50212816(9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydro...)
Affinity DataKi:  1.52E+4nMAssay Description:Displacement of [3H]PSB11 from recombinant human adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50212816(9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydro...)
Affinity DataIC50:  344nMAssay Description:Inhibition of recombinant human MAOB expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAmine oxidase [flavin-containing] B(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50212816(9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydro...)
Affinity DataIC50:  344nMAssay Description:Inhibition of human MAO-BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAmine oxidase [flavin-containing] A(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50212816(9-(3-chlorobenzyl)-1,3-dimethyl-6,7,8,9-tetrahydro...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human MAO-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed