BDBM50213418 (2E)-3-(N-hydroxycarbamoyl)-2-heptylidenepropionyl-L-tryptophan-N-methylamide::CHEMBL236446

SMILES CCCCCC\C=C(/CC(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NC

InChI Key InChIKey=QROXNPLBULDOSL-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50213418   

TargetNeutrophil collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50213418((2E)-3-(N-hydroxycarbamoyl)-2-heptylidenepropionyl...)
Affinity DataIC50: 101nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50213418((2E)-3-(N-hydroxycarbamoyl)-2-heptylidenepropionyl...)
Affinity DataIC50: 122nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50213418((2E)-3-(N-hydroxycarbamoyl)-2-heptylidenepropionyl...)
Affinity DataIC50: 123nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50213418((2E)-3-(N-hydroxycarbamoyl)-2-heptylidenepropionyl...)
Affinity DataIC50: 2.66E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50213418((2E)-3-(N-hydroxycarbamoyl)-2-heptylidenepropionyl...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50213418((2E)-3-(N-hydroxycarbamoyl)-2-heptylidenepropionyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Université

Curated by ChEMBL
LigandPNGBDBM50213418((2E)-3-(N-hydroxycarbamoyl)-2-heptylidenepropionyl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed