BDBM50213510 5-chloro-N-((1r,4r)-4-(4-(2-cyclopropoxyphenyl)piperidin-1-yl)cyclohexyl)-2-fluorobenzenesulfonamide::CHEMBL228332

SMILES O=S(=O)(N[C@H]1CC[C@H](N2CCC(c3ccccc3OC3CC3)CC2)CC1)c1cc(Cl)ccc1F

InChI Key InChIKey=LVDRNYWTLKUNNT-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50213510   

TargetAlpha-1A adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50213510BDBM50213510(5-chloro-N-((1r,4r)-4-(4-(2-cyclopropoxyphenyl)pip...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity to human cloned adrenergic alpha-1a receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1D adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50213510BDBM50213510(5-chloro-N-((1r,4r)-4-(4-(2-cyclopropoxyphenyl)pip...)
Affinity DataKi:  32nMAssay Description:Binding affinity to human cloned adrenergic alpha-1d receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50213510BDBM50213510(5-chloro-N-((1r,4r)-4-(4-(2-cyclopropoxyphenyl)pip...)
Affinity DataKi:  159nMAssay Description:Binding affinity for dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50213510BDBM50213510(5-chloro-N-((1r,4r)-4-(4-(2-cyclopropoxyphenyl)pip...)
Affinity DataKi:  337nMAssay Description:Binding affinity to human cloned adrenergic alpha-1b receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed