BDBM50213589 7-[4-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]-8-ethoxy-1,3-dimethyl-3,7-dihydropurine-2,6-dione::CHEMBL376773

SMILES CCOc1nc2n(C)c(=O)n(C)c(=O)c2n1CCCN1CCc2ccccc2C1

InChI Key InChIKey=VFEZKVLNVJQKMJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50213589   

Target5-hydroxytryptamine receptor 2A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50213589(7-[4-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]-8...)
Affinity DataKi:  590nMAssay Description:Displacement of [3H]ketanserin from rat brain 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50213589(7-[4-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]-8...)
Affinity DataKi:  1.07E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from rat brain 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50213589(7-[4-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]-8...)
Affinity DataKi:  5.75E+3nMAssay Description:Displacement of [3H]5CT from 5HT7 receptor in Wistar rat hyphalamic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed