BDBM50213956 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(4-(ethoxymethyl)benzoyl)-N-hydroxypiperidine-3-carboxamide::CHEMBL250504

SMILES CCOCc1ccc(cc1)C(=O)N1CCCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(C1)C(=O)NO

InChI Key InChIKey=OAXXNDPRBWJXOJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50213956   

LigandPNGBDBM50213956(3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(4-(...)
Affinity DataIC50: 3nMAssay Description:Inhibition of TACE by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50213956(3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(4-(...)
Affinity DataIC50: 470nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50213956(3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(4-(...)
Affinity DataIC50: 940nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50213956(3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(4-(...)
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed