BDBM50214220 CHEMBL251555::N-(5-((R)-3-((S)-1-(3,4-bis(difluoromethoxy)phenyl)-3-phenylpropylamino)-2-hydroxypropyl)-2-hydroxyphenyl)methanesulfonamide

SMILES CS(=O)(=O)Nc1cc(C[C@@H](O)CN[C@@H](CCc2ccccc2)c2ccc(OC(F)F)c(OC(F)F)c2)ccc1O

InChI Key InChIKey=GRSIQKKNSPHJED-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50214220   

TargetBeta-3 adrenergic receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50214220(N-(5-((R)-3-((S)-1-(3,4-bis(difluoromethoxy)phenyl...)
Affinity DataKi:  59nMAssay Description:Displacement of [125I]iodocyanopindolol from cloned human adrenergic beta-3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50214220(N-(5-((R)-3-((S)-1-(3,4-bis(difluoromethoxy)phenyl...)
Affinity DataKi:  71nMAssay Description:Displacement of [125I]iodocyanopindolol from human cloned adrenergic beta-2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50214220(N-(5-((R)-3-((S)-1-(3,4-bis(difluoromethoxy)phenyl...)
Affinity DataKi:  490nMAssay Description:Displacement of [125I]iodocyanopindolol from human cloned adrenergic beta-1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed