BDBM50214707 9-(5',5'-Difluoro-5'-phosphonopentyl)-9-deazaguanine::CHEMBL236709
SMILES Nc1nc2c(CCCCC(F)(F)P(O)(O)=O)c[nH]c2c(=O)[nH]1
InChI Key InChIKey=OISKFAFOKMNXNK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50214707
TargetPurine nucleoside phosphorylase(Human)
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of human PNP in presence of 0.025 mM phosphateMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Human)
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of human erythrocyte PNP assessed as inhibition of 7-methylguanosine phosphorolysis after 50 mins by spectrophotometry in presence of 0.02...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bovine)
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of calf spleen PNP assessed as inhibition of 7-methylguanosine phosphorolysis after 50 mins by spectrophotometry in presence of 0.025 mM i...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bovine)
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of calf PNP in presence of 0.025 mM phosphateMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bovine)
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Affinity DataKi: 4.40nMAssay Description:Inhibition of calf spleen PNP assessed as inhibition of 7-methylguanosine phosphorolysis after 50 mins by spectrophotometry in presence of 1 mM inorg...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bovine)
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Affinity DataKi: 6.90nMAssay Description:Inhibition of bovine PNP using 7-methylguanosine as substrate by spectrophotometric based coupled assayMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Human)
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Inhibition of human erythrocyte PNP assessed as inhibition of 7-methylguanosine phosphorolysis after 50 mins by spectrophotometry in presence of 1 mM...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Human)
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Affinity DataIC50: 20.4nMAssay Description:Inhibition of human erythrocyte PNP assessed as inhibition of 25 uM 7-methylguanosine phosphorolysis by spectrophotometry in presence of 1 mM inorgan...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bovine)
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Affinity DataIC50: 10.2nMAssay Description:Inhibition of calf spleen PNP assessed as inhibition of 25 uM 7-methylguanosine phosphorolysis by spectrophotometry in presence of 1 mM inorganic pho...More data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Human)
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Affinity DataIC50: 20.4nMAssay Description:Inhibition of human PNP in presence of 1 mM phosphateMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bovine)
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Affinity DataIC50: 10.2nMAssay Description:Inhibition of calf PNP in presence of 1 mM phosphateMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Bovine)
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Affinity DataKd: 0.100nMAssay Description:Binding affinity to calf recombinant PNP expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetry/ fluorimetric titration analysi...More data for this Ligand-Target Pair