BDBM50214854 3-((5-(6-ethylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl)methylamino)benzonitrile::CHEMBL229547

SMILES CCc1cccc(n1)-c1nc(CNc2cccc(c2)C#N)[nH]c1-c1ccc2nccnc2c1

InChI Key InChIKey=XBZPZCSZHYZEBC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50214854   

TargetTGF-beta receptor type-1(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50214854(3-((5-(6-ethylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H...)
Affinity DataIC50:  119nMAssay Description:Antagonistic activity at TGFBR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTGF-beta receptor type-1(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50214854(3-((5-(6-ethylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H...)
Affinity DataIC50:  119nMAssay Description:Inhibition of human recombinant ALK5 phosphorylation expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed