BDBM50214869 4-((4-(benzo[d][1,3]dioxol-5-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methylamino)benzamide::CHEMBL229597

SMILES Cc1cccc(n1)-c1nc(CNc2ccc(cc2)C(N)=O)[nH]c1-c1ccc2OCOc2c1

InChI Key InChIKey=RHCFFZIVATXZJH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50214869   

TargetTGF-beta receptor type-1(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50214869(4-((4-(benzo[d][1,3]dioxol-5-yl)-5-(6-methylpyridi...)
Affinity DataIC50:  262nMAssay Description:Antagonistic activity at TGFBR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTGF-beta receptor type-1(Human)
Northeastern Ohio Universities Colleges of Medicine and Pharmacy

Curated by ChEMBL
LigandPNGBDBM50214869(4-((4-(benzo[d][1,3]dioxol-5-yl)-5-(6-methylpyridi...)
Affinity DataIC50:  262nMAssay Description:Inhibition of human recombinant ALK5 phosphorylation expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed